Could a “universal vaccine” end COVID pandemics? The army is counting on it


The Army’s COVID vaccine has been tested on mice, hamsters, primates and humans.

sergeant. Tanis Kilgore/US Army

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The recent spectacular outbreak of COVID-19[female[feminine cases due to the rise of omicron variant changed the meaning of “fully vaccinated.” Many experts are now talking about annual COVID booster shots or variant-specific vaccines. But what if there was a universal coronavirus vaccine that protected against omicron and all new variants of COVID-19?

Several institutions – including the University of Wisconsin, Duke University and Brigham and Women’s Hospital in Boston – are studying pan-coronavirus vaccines, but the US military is the first to demonstrate positive test results.

the The army just announced that its pan-coronavirus vaccine, the Ferritin Nanoparticle COVID-19 Vaccine (aka SpFN) had completed Phase 1 of human trials. Publication of the results is expected in January, depending on the completion of the official analysis of the data.

Dr. Kayvon Modjarrad, director of infectious diseases at the Walter Reed Army Institute of Research (WRAIR) and co-inventor of SpFN, said defense one, “We are testing our vaccine against all the different variants, including the omicron”, the strain causing breakthrough infections even in people who received booster shots.

We’ll share what we know about pan-coronavirus vaccines and the military’s COVID-19 vaccine, including how it works and when it might become available.

To find out more, inquire free home COVID tests, why shouldn’t you”end the COVID“, mix and match booster shots, and the difference between N95, KN95 and KF94 masks.

Why do we need a pan-coronavirus vaccine?

White House chief medical adviser Dr. Anthony Fauci recently touted the importance of a universal vaccine to protect against all variants of COVID. In one interview with NBC, Fauci said that a universal COVID vaccine “would mean that the initial vaccination would cover all these little variants, so you wouldn’t have to worry.”

“We want a pan-coronavirus vaccine so you have it on the shelf to respond to the next viral pandemic,” Fauci said. “At the end of the day, you want to get a vaccine that covers everything.”

Fauci’s organization, the National Institute of Allergy and Infectious Diseases, has pledged to achieve this goal in the fall of 2021, awarding $36.3 million to three academic organizations — Duke University, University of Wisconsin and Boston’s Brigham and Women’s Hospital — to develop and research pan-coronavirus vaccines. CalTech also announced strong early results for its universal “mosaic nanoparticle” vaccine.

What is the US Army’s COVID vaccine?

The three COVID-19 vaccines currently licensed for use in the United States take two approaches to preventing infection: The use of Pfizer and Moderna vaccines mRNA to boost immunity, while the Johnson & Johnson vaccine uses a harmless rhinovirus to train the body’s immune system to respond to COVID.

The Spike Ferritin Nanoparticle COVID-19 vaccine, or SpFN, takes a third approach, using a harmless part of the COVID-19 virus to boost the body’s defenses against COVID.

SpFN also has less restrictive storage and handling requirements than Moderna and Pfizer vaccines, allowing it to be used in a wider variety of situations. It can be stored between 36 and 46 degrees Fahrenheit for up to six months and at room temperature for up to one month. according to military scientists. Pfizer’s vaccine requires an ultracold freezer (between minus 112 and minus 76 degrees F) for shipping and storage and is only stable for 31 days when stored in the refrigerator.

The army vaccine was tested with two injections, 28 days apart, and also with a third injection after six months.

How does the army vaccine against COVID-19 and other coronaviruses work?

Vaccines from Moderna, Pfizer and Johnson & Johnson all target the specific virus – SARS-CoV-2 – that causes COVID-19. But Army scientists designed their vaccine to protect against future strains of COVID as well as other coronaviruses.

The Army’s SpFN vaccine is shaped like a 24-sided soccer ball. Scientists can attach the spikes of multiple strains of coronavirus to each of the different faces, allowing them to customize the vaccine for any new variants of COVID that arise.

“The accelerated emergence of human coronaviruses over the past two decades and the rise of SARS-CoV-2 variants, including the most recently omicron, underscore the continued need for next-generation preemptive vaccines that confer broad protection against coronavirus diseases,” Modjarrad said. said in a December statement. “Our strategy has been to develop a ‘pan-coronavirus’ vaccine technology that could potentially provide safe, effective and long-lasting protection against multiple strains and species of coronavirus.”

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When will the Army’s COVID vaccine be available?

No date has been set. SpFN successfully completed animal testing and completed Phase 1 of human trials in December, but has yet to complete Phase 2 and 3 of human testing, when its safety and efficacy are compared current vaccine options.

Normally, the completion of all three phases can take up to five years, but the urgency of the COVID-19 pandemic is accelerating the process. Moderna, Pfizer, and Johnson & Johnson vaccines, for example, have been tested, reviewed, and cleared by the Food and Drug Administration over the course of a year.

What happens next with the army’s SpFN vaccine?

Once the Phase 1 human trial data has been collected, analyzed and published, Phase 2 and 3 trials will begin. There is very little information so far on when or how these trials will take place or if the phases will overlap.

To follow the progress of Army vaccine trials, visit the SpFN COVID-19 Vaccine Tracker provided by the US Army Medical Research and Development Command.

For more on COVID-19, here’s what we know about how the CDC defines being fully vaccinated, How? ‘Or’ What keep your vaccine card on your phone, and what we still don’t know about the virus After two years.

The information in this article is for educational and informational purposes only and is not intended to constitute medical or health advice. Always consult a physician or other qualified health care provider with any questions you may have about a medical condition or health goals.


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